Case Report

Vol. 34 No. 3 (2019): The Archives of Rheumatology
DOI: https://doi.org/10.5606/ArchRheumatol.2019.7070

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Published: Sep 30, 2019
Keywords:
Immunoglobulin G4-related disease, Mikulicz’s disease, thrombocytopenia
How to Cite
Shu LI, Cong DENG, Jinwei CHEN, & Fen LI. (2019). Mikulicz’s Disease With Immune Thrombocytopenia: A New Immunoglobulin G4-Mediated Disorder and Literature Review. Archives of Rheumatology, 34(3), 343–347. https://doi.org/10.5606/ArchRheumatol.2019.7070

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Shu LI
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
Cong DENG
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
Jinwei CHEN
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
Fen LI
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China

Mikulicz’s Disease With Immune Thrombocytopenia: A New Immunoglobulin G4-Mediated Disorder and Literature Review

Main Article Content

Shu LI
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
Cong DENG
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
Jinwei CHEN
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China
Fen LI
Department of Rheumatology and Immunology, The Second Xiangya Hospital, Central South University, Changsha, China

Abstract

Mikulicz’s disease (MD), an immunoglobulin G4 (IgG4)-related disease, is a fibrosis-associated inflammatory disease characterized by painless bilat- eral swelling of lacrimal and salivary glands. Although thrombocytopenia is associated with many rheumatologic disorders, it is rare in IgG4-related MD. This novel study aims to report a rare case of IgG4-related MD complicated with severe autoimmune thrombocytopenia without any hemato- logical malignancies and review all cases of IgG4-related disease associated with thrombocytopenia in the literature.

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