ISSN 1302-6631
 

Case Report 


Combined use of two depot formed antipsychotics in the treatment of resistant schizophrenia: Case report

İbrahim Yağcı, Ali İnaltekin, Yüksel Kıvrak.

Abstract
While the majority of patients diagnosed with schizophrenia have an acceptable improvement with classical anti-psychotics, it is observed that about 20% have resistance to treatment. Dual oral antipsychotic treatment may be used in patients who are resistant to treatment and the rates of use of this treatment regimen are increasing day by day. Although treatment guidelines do not recommend polypharmacy in antipsychotics in routine practice, they re-commend it for a short time after clozapine or when switching from one antipsychotic to another antipsychotic. Dual antipsychotic treatment is frequently used in the treatment of schizophrenia, whereas the use of dual depot anti-psychotics is not preferred in clinical practice. In this article, we present a case of schizophrenia treated with the combination of paliperidone and zuclopenthixol depot forms.

Key words: Antipsychotic Drugs, parenteral, schizophrenia, paliperidone palmitate, zuclopenthixol



Dirençli şizofreni tedavisinde iki depo antipsikotiğin birlikte kullanımı: Olgu sunumu

Ozet
Şizofreni hastalarının büyük bir kısmında klasik antipsikotiklerle kabul edilebilir bir iyileşme sağlanırken, yaklaşık %20’sinde tedaviye direnç görülmektedir. Tedaviye dirençli hastalarda ikili oral antipsikotik tedavi kullanılabilmekte-dir ve bu tedavi rejiminin kullanım oranları gün geçtikçe artmaktadır. Antipsikotiklerde polifarmasiyi tedavi kılavuzları rutin uygulamada önermemekle birlikte, klozapinden sonra veya bir antipsikotikten başka bir antipsikotik ilaca geçiş sırasında kısa süreli olarak önermektedir. Oral olarak ikili antipsikotik tedavi şizofreni olgularında tedavide sık olarak kullanılmakta iken, ikili depo antipsikotik kullanımı klinik uygulamalarda kullanılmamaktadır. Bu yazıda paliperidon palmitat ve zuklopentiksol depo formlarının birlikte kullanılması ile tedavi edilen bir şizofreni olgusu sunulmuştur.

Anahtar Kelimeler: Antipsikotik ilaçlar, parenteral, şizofreni, paliperidon palmitat, zuklopentiksol


 
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How to Cite this Article
Pubmed Style

Yagci I, Inaltekin A, Kivrak Y. [Combined use of two depot formed antipsychotics in the treatment of resistant schizophrenia: Case report]. Turkish. doi:10.5455/apd.82255


Web Style

Yagci I, Inaltekin A, Kivrak Y. [Combined use of two depot formed antipsychotics in the treatment of resistant schizophrenia: Case report]. http://www.anadolupsikiyatri.net/?mno=82255 [Access: April 01, 2020]. Turkish. doi:10.5455/apd.82255


AMA (American Medical Association) Style

Yagci I, Inaltekin A, Kivrak Y. [Combined use of two depot formed antipsychotics in the treatment of resistant schizophrenia: Case report]. Turkish. doi:10.5455/apd.82255



Vancouver/ICMJE Style

Yagci I, Inaltekin A, Kivrak Y. [Combined use of two depot formed antipsychotics in the treatment of resistant schizophrenia: Case report]. Turkish. doi:10.5455/apd.82255



Harvard Style

Yagci, I., Inaltekin, . A. & Kivrak, . Y. (2020) [Combined use of two depot formed antipsychotics in the treatment of resistant schizophrenia: Case report]. Turkish. doi:10.5455/apd.82255



Turabian Style

Yagci, Ibrahim, Ali Inaltekin, and Yuksel Kivrak. 2020. [Combined use of two depot formed antipsychotics in the treatment of resistant schizophrenia: Case report]. Turkish. doi:10.5455/apd.82255



Chicago Style

Yagci, Ibrahim, Ali Inaltekin, and Yuksel Kivrak. "[Combined use of two depot formed antipsychotics in the treatment of resistant schizophrenia: Case report]." Turkish. doi:10.5455/apd.82255



MLA (The Modern Language Association) Style

Yagci, Ibrahim, Ali Inaltekin, and Yuksel Kivrak. "[Combined use of two depot formed antipsychotics in the treatment of resistant schizophrenia: Case report]." Turkish. doi:10.5455/apd.82255



APA (American Psychological Association) Style

Yagci, I., Inaltekin, . A. & Kivrak, . Y. (2020) [Combined use of two depot formed antipsychotics in the treatment of resistant schizophrenia: Case report]. Turkish. doi:10.5455/apd.82255