ISSN 1302-6631
 

Case Report 


Successful management of methylphenidate related thrombocytopenia during ADHD treatment: a case report

Hüsna Kaan, Ali Karayağmurlu.

Abstract
Methylphenidate is an effective and well-tolerated agent frequently used in the treatment of attention deficit hyperactivity disorder. Thrombocytopenia is defined as a blood platelet count less than 150,000/mm3 and is an important hematological side-effect capable of causing mild symptoms or severe complications such as intracranial hemorrhage. Thrombocytopenia may develop in association with various causes, including drug use. There have been very few case reports of thrombocytopenia developing during methylphenidate use, and to the best of our knowledge, there have been no reports concerning the management of this side-effect. This report describes the development of thrombocytopenia likely related to methylphenidate therapy in an adolescent with attention deficit hyperactivity disorder and successful management with a safety switch to atomoxetine

Key words: Attention Deficit Hyperactivity Disorder, Methylphenidate, Thrombocytopenia, Atomoxetine



Metilfenidat kullanımı sonrası trombositopeni gelişen bir ergen olguda atomoksetine güvenli bir geçiş: Olgu sunumu

Ozet
Metilfenidat, dikkat eksikliği hiperaktivite bozukluğu tedavisinde sık kullanılan etkili ve güvenilir bir ajandır. Trombositopeni kandaki trombosit sayısının 150.000/mm3’ten az olmasıdır. Trombositopeni, asemptomatik gidişten kafa içi kanamalar gibi ciddi komplikasyonlara neden olabilen önemli bir hematolojik sorundur. Trombositopenin ilaç kullanımı da dahil olmak üzere birçok nedene bağlı olarak gelişebildiği bilinmektedir. Metilfenidat kullanımı sırasında trombositopeni gelişimi ile ilgili az sayıda olgu bildirimi vardır ve bildiğimiz kadarıyla bu yan etkinin yönetilmesi ile ilgili herhangi bir olgu bildirimine rastlanmamıştır. Bu yazıda, DEHB’li bir ergen olguda olasılıkla metilfenidat kullanmaya bağlı trombositopeni gelişimi ve bu durumun atomoksetine güvenli bir geçiş yapılarak başarılı bir şekilde yönetilmesi sunulmuştur.

Anahtar Kelimeler: Dikkat eksikliği hiperaktivite bozukluğu, metilfenidat, trombositopeni, atomoksetin


 
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How to Cite this Article
Pubmed Style

Kaan H, Karayagmurlu A. Successful management of methylphenidate related thrombocytopenia during ADHD treatment: a case report. doi:10.5455/apd.78877


Web Style

Kaan H, Karayagmurlu A. Successful management of methylphenidate related thrombocytopenia during ADHD treatment: a case report. http://www.anadolupsikiyatri.net/?mno=78877 [Access: April 04, 2020]. doi:10.5455/apd.78877


AMA (American Medical Association) Style

Kaan H, Karayagmurlu A. Successful management of methylphenidate related thrombocytopenia during ADHD treatment: a case report. doi:10.5455/apd.78877



Vancouver/ICMJE Style

Kaan H, Karayagmurlu A. Successful management of methylphenidate related thrombocytopenia during ADHD treatment: a case report. doi:10.5455/apd.78877



Harvard Style

Kaan, H. & Karayagmurlu, . A. (2020) Successful management of methylphenidate related thrombocytopenia during ADHD treatment: a case report. doi:10.5455/apd.78877



Turabian Style

Kaan, Husna, and Ali Karayagmurlu. 2020. Successful management of methylphenidate related thrombocytopenia during ADHD treatment: a case report. doi:10.5455/apd.78877



Chicago Style

Kaan, Husna, and Ali Karayagmurlu. "Successful management of methylphenidate related thrombocytopenia during ADHD treatment: a case report." doi:10.5455/apd.78877



MLA (The Modern Language Association) Style

Kaan, Husna, and Ali Karayagmurlu. "Successful management of methylphenidate related thrombocytopenia during ADHD treatment: a case report." doi:10.5455/apd.78877



APA (American Psychological Association) Style

Kaan, H. & Karayagmurlu, . A. (2020) Successful management of methylphenidate related thrombocytopenia during ADHD treatment: a case report. doi:10.5455/apd.78877