ISSN 1302-6631
 

Case Report 


Trazodon kullanımı ile ilişkili galaktore ve hiperprolaktinemi: Olgu sunumu

Hüseyin Murat Ozkan .

Abstract
Trazodone was the first second-generation antidepressant; it is a weak inhibitor of serotonin reuptake but a strong antagonist of serotonin type 2A (5HT2A) and type 2C (5HT2C) receptors. Galactorrhea associated with antidepressant use has rarely been reported in the literature. To our knowledge, this is the second case report of galactorrhea associated with trazodone use so far. Here, we report the case of a patient treated with duloxetine and quetiapine for 5 months; however, quetiapine was discontinued because of dizziness and drowsiness. Quetiapine was replaced with trazadone; however, we observed that the patient developed galactorrhea within 4 weeks of treatment initiation.

Key words: Trazodone, Galactorrhea, Hyperprolactinemia



Trazodon kullanımı ile ilişkili galaktore ve hiperprolaktinemi: Olgu sunumu

Ozet
Trazodon, ikinci kuşak antidepresanların ilki olup zayıf serotonin geri alım inhibitörü ve serotonin tip 2A (5HT2A) ve tip 2C (5HT2C) reseptörlerinin güçlü bir antagonistidir. Literatürde antidepresanlarla ilişkili galaktore görülmesi nadir olarak bildirilmiş olup bu konudaki yayınlar olgu sunumları ile sınırlıdır. Bilgilerimize göre, şimdiye kadar bildirilmiş olan trazodonla ilişkili galaktore görülen ikinci olgu sunumudur. Depresyon tanısı ile izlediğimiz olgumuzda dulok-setin ve ketiyapin ile tedavinin beşinci ayında, olgunun sabah uyanmakta zorluk ve sersemlik yakınmaları nedeniyle ketiyapin sonlandırılmış yerine trazodon başlanmıştır. Trazodon eklenmesinden dört hafta sonrasında olguda bu defa galaktore yakınması gelişmiştir.

Anahtar Kelimeler: Trazodon, Galaktore, Hiperprolaktinemi


 
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Pubmed Style

HMO, . [Trazodon kullanımı ile ilişkili galaktore ve hiperprolaktinemi: Olgu sunumu]. Anadolu Psikiyatri Derg. 2019; 20(3): 333-335. Turkish. doi:10.5455/apd.38827


Web Style

HMO, . [Trazodon kullanımı ile ilişkili galaktore ve hiperprolaktinemi: Olgu sunumu]. http://www.anadolupsikiyatri.net/?mno=38827 [Access: July 20, 2019]. Turkish. doi:10.5455/apd.38827


AMA (American Medical Association) Style

HMO, . [Trazodon kullanımı ile ilişkili galaktore ve hiperprolaktinemi: Olgu sunumu]. Anadolu Psikiyatri Derg. 2019; 20(3): 333-335. Turkish. doi:10.5455/apd.38827



Vancouver/ICMJE Style

HMO, . [Trazodon kullanımı ile ilişkili galaktore ve hiperprolaktinemi: Olgu sunumu]. Anadolu Psikiyatri Derg. (2019), [cited July 20, 2019]; 20(3): 333-335. Turkish. doi:10.5455/apd.38827



Harvard Style

, H. M. O. & (2019) [Trazodon kullanımı ile ilişkili galaktore ve hiperprolaktinemi: Olgu sunumu]. Anadolu Psikiyatri Derg, 20 (3), 333-335. Turkish. doi:10.5455/apd.38827



Turabian Style

, Huseyin Murat Ozkan, and . 2019. [Trazodon kullanımı ile ilişkili galaktore ve hiperprolaktinemi: Olgu sunumu]. Anatolian Journal of Psychiatry, 20 (3), 333-335. Turkish. doi:10.5455/apd.38827



Chicago Style

, Huseyin Murat Ozkan, and . "[Trazodon kullanımı ile ilişkili galaktore ve hiperprolaktinemi: Olgu sunumu]." Anatolian Journal of Psychiatry 20 (2019), 333-335. Turkish. doi:10.5455/apd.38827



MLA (The Modern Language Association) Style

, Huseyin Murat Ozkan, and . "[Trazodon kullanımı ile ilişkili galaktore ve hiperprolaktinemi: Olgu sunumu]." Anatolian Journal of Psychiatry 20.3 (2019), 333-335. Print.Turkish. doi:10.5455/apd.38827



APA (American Psychological Association) Style

, H. M. O. & (2019) [Trazodon kullanımı ile ilişkili galaktore ve hiperprolaktinemi: Olgu sunumu]. Anatolian Journal of Psychiatry, 20 (3), 333-335. Turkish. doi:10.5455/apd.38827





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