ISSN 1302-6631
 

Original Research (Original Article) 


Are treatment adherence and insight related to quality of life in patients with schizophrenia and bipolar disorder in remission?

Aysun Demir Özdemir, Leman İnanç, Merih Altıntaş, Hüseyin Güleç, Ümit Başar Semiz.

Abstract
Objectives: The aim of this study is to investigate the association of treatment adherence, quality of life and insight among bipolar disorder and schizophrenia patients who are in remission and to reveal which variables predict the treatment adherence. Methods: We conducted a cross sectional study with 150 schizophrenia and 150 bipolar disorder patients in remission. The patients were administered Mini International Neuropsychiatric Interview (MINI), Brief Psychiatric Rating Scale (BPRS), the Schedule for Assessing the Three Components of Insight (SAI), World Health Organization Questionnaire on Quality of Life: Short Form (WHOQOL-BREF), Medication Adherence Rating Scale (MARS). We compared WHOQOL-BREF scores of the bipolar and schizophrenia patients. We checked the correlation between SAI scores and BPRS scores as well as between SAI scores and WHOQOL-BREF scores for both groups. We set MARS results (adherent vs. non-adherent) as a dependent variable and conducted logistic regression with all the clinical variables available to find a predictor for treatment adherence. Results: WHOQOL-BREF scores were found to be similar and positively correlated with insight for both groups. BPRS scores were found to be negatively correlated with insight for both groups. SAI treatment acceptance was found to be the only predictor of treatment adherence independent of the other clinical variables. Discussion: A strong positive rela-tionship between insight and treatment adherence suggests that treatment adherence of patients with good insight is better. The positive relationship between insight and quality of life shows that insight is an important factor in terms of quality of life and reveals the importance of insight oriented therapies.

Key words: Treatment adherence, schizophrenia, bipolar disorder type I, insight, quality of life



Remisyondaki şizofreni ve bipolar bozukluk hastalarında tedavi uyumu ve iç görü, yaşam kalitesi ile ilişkili midir?

Ozet
Amaç: Bu çalışmanın amacı, remisyon dönemindeki şizofreni ve bipolar I bozukluk hastalarında tedavi uyumunun, iç görü ve yaşam kalitesi ile ilişkisini açıklamak ve bu değişkenlerin tedavi uyumunu hangi ölçüde yordadığını ortaya koymaktır. Yöntem: Remisyondaki 150 şizofreni ve 150 bipolar bozukluk hastasıyla kesitsel bir çalışma yapıldı. Hastalara İçgörünün Üç Bileşenini Değerlendirme Ölçeği, Mini Uluslararası Psikiyatrik Görüşme (MINI), Kısa Psiki-yatrik Değerlendirme Ölçeği (KPDÖ), Dünya Sağlık Örgütü Yaşam Kalitesi Ölçeği Kısa Formu Türkçe Versiyonu, MARS Tıbbi Tedaviye Uyum Oranı Ölçeği uygulandı. Bipolar ve şizofreni hastalarının yaşam kalitesi puanlarını karşılaştırdık. İçgörünün Üç Bileşenini Değerlendirme Ölçeği puanları ile KPDÖ puanları arasındaki korelasyonun yanı sıra iç görü puanları ile yaşam kalitesi skorları arasındaki korelasyonu kontrol ettik. Bağımlı bir değişken olarak MARS sonuçlarını değerlendirerek, tedavi uyumu için bir öngördürücü olup olmadığını araştırmak amacıyla, tüm klinik değişkenleri içerecek şekilde lojistik regresyon uyguladık. Bulgular: Yaşam kalitesi ölçeği puanlarının iki grup için de benzer ve iç görü ile pozitif korele olduğu bulundu. KPDÖ puanlarının her iki grup için de iç görüyle negatif korele olduğu bulundu. İçgörünün Üç Bileşenini Değerlendirme Ölçeği tedavi kabulü alt ölçeği, diğer klinik değiş-kenlerden bağımsız olarak tedaviye uyumun tek göstergesi olarak bulunmuştur. Tartışma: İç görü ve tedavi uyumu arasında güçlü pozitif ilişki, iç görüsü iyi olan hastaların tedaviye uyumlarının daha iyi olduğunu düşündürmektedir. İç görü ve yaşam kalitesi arasındaki pozitif ilişki iç görünün yaşam kalitesi açısından önemli bir etken olduğunu göstermekte ve iç görü kazandırmaya yönelik terapilerin önemini ortaya koymaktadır.

Anahtar Kelimeler: Tedavi uyumu, Şizofreni, bipolar I bozukluk, içgörü, yaşam kalitesi


 
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Pubmed Style

Ozdemir AD, Inanc L, Altintas M, Gulec H, Semiz UB. Are treatment adherence and insight related to quality of life in patients with schizophrenia and bipolar disorder in remission?. Anadolu Psikiyatri Derg. 2018; 19(5): 443-450. doi:10.5455/apd.290161


Web Style

Ozdemir AD, Inanc L, Altintas M, Gulec H, Semiz UB. Are treatment adherence and insight related to quality of life in patients with schizophrenia and bipolar disorder in remission?. http://www.anadolupsikiyatri.net/?mno=290161 [Access: September 21, 2018]. doi:10.5455/apd.290161


AMA (American Medical Association) Style

Ozdemir AD, Inanc L, Altintas M, Gulec H, Semiz UB. Are treatment adherence and insight related to quality of life in patients with schizophrenia and bipolar disorder in remission?. Anadolu Psikiyatri Derg. 2018; 19(5): 443-450. doi:10.5455/apd.290161



Vancouver/ICMJE Style

Ozdemir AD, Inanc L, Altintas M, Gulec H, Semiz UB. Are treatment adherence and insight related to quality of life in patients with schizophrenia and bipolar disorder in remission?. Anadolu Psikiyatri Derg. (2018), [cited September 21, 2018]; 19(5): 443-450. doi:10.5455/apd.290161



Harvard Style

Ozdemir, A. D., Inanc, L., Altintas, M., Gulec, H. & Semiz, U. B. (2018) Are treatment adherence and insight related to quality of life in patients with schizophrenia and bipolar disorder in remission?. Anadolu Psikiyatri Derg, 19 (5), 443-450. doi:10.5455/apd.290161



Turabian Style

Ozdemir, Aysun Demir, Leman Inanc, Merih Altintas, Huseyin Gulec, and Umit Basar Semiz. 2018. Are treatment adherence and insight related to quality of life in patients with schizophrenia and bipolar disorder in remission?. Anatolian Journal of Psychiatry, 19 (5), 443-450. doi:10.5455/apd.290161



Chicago Style

Ozdemir, Aysun Demir, Leman Inanc, Merih Altintas, Huseyin Gulec, and Umit Basar Semiz. "Are treatment adherence and insight related to quality of life in patients with schizophrenia and bipolar disorder in remission?." Anatolian Journal of Psychiatry 19 (2018), 443-450. doi:10.5455/apd.290161



MLA (The Modern Language Association) Style

Ozdemir, Aysun Demir, Leman Inanc, Merih Altintas, Huseyin Gulec, and Umit Basar Semiz. "Are treatment adherence and insight related to quality of life in patients with schizophrenia and bipolar disorder in remission?." Anatolian Journal of Psychiatry 19.5 (2018), 443-450. Print. doi:10.5455/apd.290161



APA (American Psychological Association) Style

Ozdemir, A. D., Inanc, L., Altintas, M., Gulec, H. & Semiz, U. B. (2018) Are treatment adherence and insight related to quality of life in patients with schizophrenia and bipolar disorder in remission?. Anatolian Journal of Psychiatry, 19 (5), 443-450. doi:10.5455/apd.290161





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