ISSN 1302-6631
 

Original Research (Original Article) 


A cross-sectional study comparing some clinical features of patients with rapid cycling and non-rapid cycling bipolar disorder

Murat Eren Özen, Mehmet Bertan Yılmaz.

Abstract
Objective: Literature indicates that rapid cycling (RC) feature in bipolar disorder (BD) has been associated with worse disorder outcome and more severe disability. We aimed to investigate factors that affect or involved in vulnerability to increase rapid cycling in the previous 12 months. Methods: This is a cross-sectional study. Patients (n=380) were recruited from an outpatients clinic of a general hospital. Diagnostic interviews were performed with Structured Clinical Interview for DSM-IV Disorders (SCID-I) and SCID-II. Sociodemographic Form, Young Mania Rating Scale (YMRS) and Hamilton Depression Rating Scale (HAM-D) were applied. RC was defined as presence four or more mood episodes in the previous 12 months. Patients were arranged as whether having rapid cycling bipolar disorder (RCBD) or not. RCBD was compared to the group of non-RCBD patients regarding the sociode-mographic and clinical data. Results: Study group showed a female preponderance (65.0%). Sixty patients (15.8%) had RC in the previous 12 months. There were statistically significant differences between two groups regarding in number of suicide attempts, family history of mood disorders, psychotic depression, number of antidepressants utilized, manic, depressive, mixed and total number of episodes. Discussion: The presence of RC in the previous 12 months was found correlated with specific clinical features closely related to worse outcome in the course of BD. Further studies are needed to clarify disease-related factors in patient groups with a standard definition of homo-geneous RCBD.

Key words: bipolar disorder, rapid cycling, clinical variables



Hızlı döngülü ve hızlı olmayan bipolar bozukluk hastalarının bazı klinik özelliklerini karşılaştıran kesitsel bir çalışma

Ozet
Amaç: Literatür, bipolar bozuklukta (BB) hızlı döngü özelliğinin (HD) daha kötü hastalık sonucu ve daha ciddi malu-liyet ile ilişkili olduğunu göstermektedir. Son 12 ayda HD'yi etkileyen veya artmasında etkili etkenleri araştırmayı amaçladık. Yöntem: Bu bir kesitsel çalışmadır. Hastalar (s=380) genel bir hastanenin polikliniklerinden alındı. Tanı görüşmelerinde DSM-IV Bozuklukları için Yapılandırılmış Klinik Görüşme (SCID-I) ve SCID-II uygulandı. Sosyode-mografik Form, Young Mani Derecelendirme Ölçeği (YMRS) ve Hamilton Depresyon Ölçeği (HDÖ) uygulandı. HD, önceki 12 ayda dört veya daha fazla duygudurum nöbetinin varlığı olarak tanımlandı. Hastalar hızlı döngülü bipolar bozukluk (HDBB) tanısı olup olmadıklarına göre ayrıldı. HDBB hasta grubu, HDBB olmayan hasta grubuyla sosyo-demografik ve klinik veriler açısından karşılaştırıldı. Sonuçlar: Çalışma grubunda kadınlar daha yüksek orandaydı (%65.0). Altmış hastada (%15.8) son 12 ayda HD vardı. İntihar girişimi sayısı, duygudurum bozuklukları aile öyküsü, psikotik depresyon, kullanılan antidepresan sayısı, manik, depresif, karışık ve toplam nöbet sayısı açısından iki grup grup arasında istatistiksel olarak anlamlı farklılıklar bulundu. Tartışma: Son 12 ayda HD varlığı, BB gidişinde daha kötü sonuçlarla yakından ilişkili özgül klinik özellikler ile ilişkili bulundu. Standart tanımı yapılmış ve homojen HDBB hasta gruplarında hastalıkla ilişkili etkenlerin açığa çıkartılması için daha fazla çalışmaya gerek vardır.

Anahtar Kelimeler: Bipolar bozukluk, hızlı döngü, klinik değişkenler


 
ARTICLE TOOLS
Abstract
PDF Fulltext
Print this article Print this Article
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Murat Eren Özen
Articles by Mehmet Bertan Yılmaz
on Google
on Google Scholar
Article Statistics
 Viewed: 1514
Downloaded: 233
Cited: 0


How to Cite this Article
Pubmed Style

Ozen ME, Yilmaz MB. A cross-sectional study comparing some clinical features of patients with rapid cycling and non-rapid cycling bipolar disorder. Anadolu Psikiyatri Derg. 2019; 20(5): 477-484. doi:10.5455/apd.22515


Web Style

Ozen ME, Yilmaz MB. A cross-sectional study comparing some clinical features of patients with rapid cycling and non-rapid cycling bipolar disorder. http://www.anadolupsikiyatri.net/?mno=22515 [Access: November 17, 2019]. doi:10.5455/apd.22515


AMA (American Medical Association) Style

Ozen ME, Yilmaz MB. A cross-sectional study comparing some clinical features of patients with rapid cycling and non-rapid cycling bipolar disorder. Anadolu Psikiyatri Derg. 2019; 20(5): 477-484. doi:10.5455/apd.22515



Vancouver/ICMJE Style

Ozen ME, Yilmaz MB. A cross-sectional study comparing some clinical features of patients with rapid cycling and non-rapid cycling bipolar disorder. Anadolu Psikiyatri Derg. (2019), [cited November 17, 2019]; 20(5): 477-484. doi:10.5455/apd.22515



Harvard Style

Ozen, M. E. & Yilmaz, . M. B. (2019) A cross-sectional study comparing some clinical features of patients with rapid cycling and non-rapid cycling bipolar disorder. Anadolu Psikiyatri Derg, 20 (5), 477-484. doi:10.5455/apd.22515



Turabian Style

Ozen, Murat Eren, and Mehmet Bertan Yilmaz. 2019. A cross-sectional study comparing some clinical features of patients with rapid cycling and non-rapid cycling bipolar disorder. Anatolian Journal of Psychiatry, 20 (5), 477-484. doi:10.5455/apd.22515



Chicago Style

Ozen, Murat Eren, and Mehmet Bertan Yilmaz. "A cross-sectional study comparing some clinical features of patients with rapid cycling and non-rapid cycling bipolar disorder." Anatolian Journal of Psychiatry 20 (2019), 477-484. doi:10.5455/apd.22515



MLA (The Modern Language Association) Style

Ozen, Murat Eren, and Mehmet Bertan Yilmaz. "A cross-sectional study comparing some clinical features of patients with rapid cycling and non-rapid cycling bipolar disorder." Anatolian Journal of Psychiatry 20.5 (2019), 477-484. Print. doi:10.5455/apd.22515



APA (American Psychological Association) Style

Ozen, M. E. & Yilmaz, . M. B. (2019) A cross-sectional study comparing some clinical features of patients with rapid cycling and non-rapid cycling bipolar disorder. Anatolian Journal of Psychiatry, 20 (5), 477-484. doi:10.5455/apd.22515





Most Viewed Articles
  • Schizophrenia and mega cisterna magna: case report [Turkish]
    Semra Karayılan, Atila Erol
    Anadolu Psikiyatri Derg. 2013; 14(1): 90-92
    » Abstract & References » doi: 10.5455/apd.36699

  • Impulsivity in patients with obesity and correlations with body perception and self-esteem [Turkish]
    G Sarısoy, A Atmaca, G Ecemiş, K Gümüş, O Pazvantoğlu
    Anadolu Psikiyatri Derg. 2013; 14(1): 53-61
    » Abstract & References » doi: 10.5455/apd.34469

  • The relationship between aggression and online video game addiction: a study on massively multiplayer online video game players [Turkish]
    H. Andaç Demirtaş Madran, Eda Ferligül Çakılcı
    Anadolu Psikiyatri Derg. 2014; 15(2): 99-107
    » Abstract & References » doi: 10.5455/apd.39828

  • The effects of the service of community mental health center on the patients with schizophrenia - evaluation of quality of life, disabilities, general and social functioning- a summary of one year follow-up [Turkish]
    Hülya Ensari, Bülent Kadri Gültekin, Derya Karaman, Ayşegül Koç, Ali Fuat Beşkardeş
    Anadolu Psikiyatri Derg. 2013; 14(2): 108-114
    » Abstract & References » doi: 10.5455/apd.36380

  • Reliability and validity of the Morisky Medication Adherence Scale for bipolar mood disorder [Turkish]
    Güven Bahar, Haluk A. Savaş, Ahmet Ünal, Esen Savaş, Hilal Kaya, Aynur Bahar
    Anadolu Psikiyatri Derg. 2014; 15(2): 141-149
    » Abstract & References » doi: 10.5455/apd.39827

  • Cases of sibling incest resulting in pregnancy [Turkish]
    Evrim Aktepe, Orhan Kocaman
    Anadolu Psikiyatri Derg. 2013; 14(2): 177-180
    » Abstract & References » doi: 10.5455/apd.35965

  • Eating disorders and psychosis [Turkish]
    Vesile Altınyazar, Fulya Maner
    Anadolu Psikiyatri Derg. 2014; 15(1): 84-88
    » Abstract & References » doi: 10.5455/apd.38073

  • The Scale of Positive and Negative Experience: a validity and reliability study for adolescents [Turkish]
    Bülent Baki Telef
    Anadolu Psikiyatri Derg. 2013; 14(1): 62-68
    » Abstract & References » doi: 10.5455/apd.36692

  • Job satisfaction and perceived job stress of the health professionals and the relationship between them [Turkish]
    Etem Erdal Erşan, Gülay Yıldırım, Orhan Doğan, Selma Doğan
    Anadolu Psikiyatri Derg. 2013; 14(2): 115-121
    » Abstract & References » doi: 10.5455/apd.34482

  • Death anxiety in elderly cases [Turkish]
    Zehra Öztürk, Gonca Karakuş, Lut Tamam
    Anadolu Psikiyatri Derg. 2011; 12(1): 37-43
    » Abstract

  • Most Downloaded
  • Regional drug abuse prevalence depending on laboratory based urine illicit drug screening results [Turkish]
    Çiğdem Karakükcü, Mehmet Zahit Çıracı, Derya Koçer, Gözde Ertürk Zararsız, Mustafa Reyhancan, İsmail Altıntop
    Anadolu Psikiyatri Derg. 2018; 19(2): 169-176
    » Abstract » doi: 10.5455/apd.264474

  • Frontal Lobe Syndrome Developing After Head Trauma: Case Report [Turkish]
    Betül Çevik, Ali Yıldırım, Dürdane Aksoy, Erdal Özer, Semiha Kurt
    Anadolu Psikiyatri Derg. 2015; 16(3): 223-226
    » Abstract & References » doi: 10.5455/apd.155354

  • Arachnoid cysts accompanied with psychiatric symptoms: Case series [Turkish]
    Sıla Yazar, Nurhan Fıstıkcı, Gülsüm Cantürk, Serap Oflaz, Ali Haydar Küçüktüfekçi, Alkin Yılmaz, Demet Yandım Kuşçu
    Anadolu Psikiyatri Derg. 2013; 14(1): 87-89
    » Abstract & References » doi: 10.5455/apd.35964

  • Schizophrenia and mega cisterna magna: case report [Turkish]
    Semra Karayılan, Atila Erol
    Anadolu Psikiyatri Derg. 2013; 14(1): 90-92
    » Abstract & References » doi: 10.5455/apd.36699

  • Educational needs assessment of stigmatization towards mental illness in medical education: qualitative and quantitative approach [Turkish]
    Meral Demirören, Yeşim Şenol, Ayşen Melek Aytuğ-Koşan, Meram Can Saka
    Anadolu Psikiyatri Derg. 2015; 16(1): 22-29
    » Abstract & References » doi: 10.5455/apd.45731

  • Thyroid gland functions are affected in obsessive-compulsive disorder [English]
    Osman Mermi, Murad Atmaca
    Anadolu Psikiyatri Derg. 2016; 17(2): 99-103
    » Abstract & References » doi: 10.5455/apd.178087

  • Translation of Big-Five Personality Questionnaire into Turkish and comparing it with Five Factor Personality Inventory Short Form [Turkish]
    Arkun Tatar
    Anadolu Psikiyatri Derg. 2017; 18(1): 51-61
    » Abstract » doi: 10.5455/apd.220580

  • Severe mental disorders, depression and smoking cessation [Turkish]
    L. İlhan Yargıç, Hayriye Baykan
    Anadolu Psikiyatri Derg. 2013; 14(1): 77-83
    » Abstract & References » doi: 10.5455/apd.34493

  • Impulsivity in patients with obesity and correlations with body perception and self-esteem [Turkish]
    G Sarısoy, A Atmaca, G Ecemiş, K Gümüş, O Pazvantoğlu
    Anadolu Psikiyatri Derg. 2013; 14(1): 53-61
    » Abstract & References » doi: 10.5455/apd.34469

  • Validity and reliability of the Turkish version of the Smartphone Addiction Scale-Short Version among university students [Turkish]
    Cemal Onur Noyan, Aslı Enez Darçın, Serdar Nurmedov, Onat Yılmaz , Nesrin Dilbaz
    Anadolu Psikiyatri Derg. 2015; 16(Supplement 1): 73-81
    » Abstract & References » doi: 10.5455/apd.176101

  • Most Cited Articles
  • Validity and reliability of the Turkish version of the Smartphone Addiction Scale-Short Version among university students [Turkish]
    Cemal Onur Noyan, Aslı Enez Darçın, Serdar Nurmedov, Onat Yılmaz , Nesrin Dilbaz
    Anadolu Psikiyatri Derg. 2015; 16(Supplement 1): 73-81
    » Abstract & References » doi: 10.5455/apd.176101
    Cited : 24 times [Click to see citing articles]

  • Psychometric properties of the Turkish version of the Yale Food Addiction Scale among bariatric surgery patients [English]
    Güzin Mukaddes Sevinçer, Numan Konuk, Süleyman Bozkurt, Özge Saraçlı, Halil Coşkun
    Anadolu Psikiyatri Derg. 2015; 16(Supplement 1): 44-53
    » Abstract & References » doi: 10.5455/apd.174345
    Cited : 11 times [Click to see citing articles]

  • Turkish adaptation of Young’s Internet Addiction Test-Short Form: a reliability and validity study on university students and adolescents [Turkish]
    Mustafa Kutlu, Mustafa Savcı, Yasin Demir, Ferda Aysan
    Anadolu Psikiyatri Derg. 2016; 17(Supplement 1): 69-76
    » Abstract & References » doi: 10.5455/apd.190501
    Cited : 11 times [Click to see citing articles]

  • The reliability and validity of Turkish version of The Night Eating Questionnaire in psychiatric outpatient population [Turkish]
    Nuray Atasoy, Özge Saraçlı, Numan Konuk, Handan Ankaralı, S. Olga Güriz, Asena Akdemir, Güzin Mukaddes Sevinçer, Levent Atik
    Anadolu Psikiyatri Derg. 2014; 15(3): 238-247
    » Abstract & References » doi: 10.5455/apd.39829
    Cited : 9 times [Click to see citing articles]

  • The effects of the service of community mental health center on the patients with schizophrenia - evaluation of quality of life, disabilities, general and social functioning- a summary of one year follow-up [Turkish]
    Hülya Ensari, Bülent Kadri Gültekin, Derya Karaman, Ayşegül Koç, Ali Fuat Beşkardeş
    Anadolu Psikiyatri Derg. 2013; 14(2): 108-114
    » Abstract & References » doi: 10.5455/apd.36380
    Cited : 8 times [Click to see citing articles]

  • Burnout, job satisfaction and depression in the healthcare personnel who work in the emergency department [Turkish]
    Cem Gökçen, Suat Zengin, Mehmet Murat Oktay, Gökay Alpak, Behçet Al, Cuma Yıldırım
    Anadolu Psikiyatri Derg. 2013; 14(2): 122-128
    » Abstract & References » doi: 10.5455/apd.36379
    Cited : 8 times [Click to see citing articles]

  • An evaluation of the quality of life of children with attention-deficit/hyperactivity disorder (ADHD) and their families [English]
    Hasan Kandemir, Birim Günay Kılıç, Suat Ekinci, Murat Yüce
    Anadolu Psikiyatri Derg. 2014; 15(3): 265-271
    » Abstract & References » doi: 10.5455/apd.46202
    Cited : 7 times [Click to see citing articles]

  • The prediction level of caregiver burden on caregivers’ state-trait anxiety levels [Turkish]
    Zümra Özyeşil, Aslin Oluk, Duran Çakmak
    Anadolu Psikiyatri Derg. 2014; 15(1): 39-44
    » Abstract & References » doi: 10.5455/apd.39820
    Cited : 7 times [Click to see citing articles]

  • The Scale of Positive and Negative Experience: a validity and reliability study for adolescents [Turkish]
    Bülent Baki Telef
    Anadolu Psikiyatri Derg. 2013; 14(1): 62-68
    » Abstract & References » doi: 10.5455/apd.36692
    Cited : 6 times [Click to see citing articles]

  • Impulsivity in patients with obesity and correlations with body perception and self-esteem [Turkish]
    G Sarısoy, A Atmaca, G Ecemiş, K Gümüş, O Pazvantoğlu
    Anadolu Psikiyatri Derg. 2013; 14(1): 53-61
    » Abstract & References » doi: 10.5455/apd.34469
    Cited : 6 times [Click to see citing articles]