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Original Research (Original Article) 


Thyroid gland functions are affected in obsessive-compulsive disorder

Osman Mermi, Murad Atmaca.

Cited by (1)

Abstract
Objective: In the present study, it was aimed to examine thyroid functions in a group of patients with OCD who had not any comorbid conditions. Methods: Our present study included forty patients diagnosed with OCD and forty healthy controls. The subjects were selected by the chart reviews among the patients with OCD who had applied to the Firat University School of Medicine Department of Psychiatry, as inpatients or outpatients and had met the criteria of the present investigation. Thyroid hormone values had been obtained by using an auto analyzer. Results: Independent t test revealed that there were no statistically significant differences thyroid stimulating hormone (TSH) values between the patients with OCD and healthy control subjects whereas there were statistically significant reduced levels of free triiodothyronine (FT3) and free thyroxine (FT4) hormones in the patient group compared to those of healthy ones. Conclusion: Consequently, altered levels of thyroid hormones may be associated with pathophysiology or maintenance of OCD.

Key words: OCD, TSH, thyroid hormones



Obsesif kompulsif bozuklukta tiroit işlevleri etkilenmektedir

Ozet
Amaç: Çalışmamızda, komorbid durumu olmayan obsesif kompulsif bozukluklu (OKB) bir grup hastada tiroit işlevlerinin incelenmesi amaçlanmıştır. Yöntem: Çalışmaya 40 OKB hastası ve 40 sağlıklı kontrol grubu alındı. Denekler, Fırat Üniversitesi Tıp Fakültesi Psikiyatri Bölümü’nde ayaktan veya yatarak tedavi gören ve çalışma ölçütlerini karşılayan OKB hastalarının dosyalarının geriye dönük taranmasıyla seçildi. Tiroit hormon değerleri oto-analizer kullanılarak elde edildi. Bulgular: Bağımsız t testi, tiroit salgılatıcı hormon (TSH) düzeylerinin OKB grubu ile sağlıklı kontrol grubu arasında istatistiksel olarak anlamlı fark olmadığını, serbest triiyodotironin (sT3) ve serbest tiroksin (sT4) düzeylerinin ise hasta grubunda, kontrol grubuna göre istatistiksel olarak anlamlı düzeyde azaldığını ortaya koymuştur. Sonuç: Sonuç olarak, tiroit hormonlarının düzeylerindeki değişiklik, OKB’nin patofizyolojisiyle veya hastalığın kliniğinin sürmesiyle ilişkili olabilir.

Anahtar Kelimeler: OKB, TSH, tiroid hormonları


 
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Pubmed Style

Osman Mermi, Murad Atmaca. Thyroid gland functions are affected in obsessive-compulsive disorder. Anadolu Psikiyatri Derg. 2016; 17(2): 99-103. doi:10.5455/apd.178087


Web Style

Osman Mermi, Murad Atmaca. Thyroid gland functions are affected in obsessive-compulsive disorder. http://www.anadolupsikiyatri.net/?mno=178087 [Access: April 21, 2019]. doi:10.5455/apd.178087


AMA (American Medical Association) Style

Osman Mermi, Murad Atmaca. Thyroid gland functions are affected in obsessive-compulsive disorder. Anadolu Psikiyatri Derg. 2016; 17(2): 99-103. doi:10.5455/apd.178087



Vancouver/ICMJE Style

Osman Mermi, Murad Atmaca. Thyroid gland functions are affected in obsessive-compulsive disorder. Anadolu Psikiyatri Derg. (2016), [cited April 21, 2019]; 17(2): 99-103. doi:10.5455/apd.178087



Harvard Style

Osman Mermi, Murad Atmaca (2016) Thyroid gland functions are affected in obsessive-compulsive disorder. Anadolu Psikiyatri Derg, 17 (2), 99-103. doi:10.5455/apd.178087



Turabian Style

Osman Mermi, Murad Atmaca. 2016. Thyroid gland functions are affected in obsessive-compulsive disorder. Anatolian Journal of Psychiatry, 17 (2), 99-103. doi:10.5455/apd.178087



Chicago Style

Osman Mermi, Murad Atmaca. "Thyroid gland functions are affected in obsessive-compulsive disorder." Anatolian Journal of Psychiatry 17 (2016), 99-103. doi:10.5455/apd.178087



MLA (The Modern Language Association) Style

Osman Mermi, Murad Atmaca. "Thyroid gland functions are affected in obsessive-compulsive disorder." Anatolian Journal of Psychiatry 17.2 (2016), 99-103. Print. doi:10.5455/apd.178087



APA (American Psychological Association) Style

Osman Mermi, Murad Atmaca (2016) Thyroid gland functions are affected in obsessive-compulsive disorder. Anatolian Journal of Psychiatry, 17 (2), 99-103. doi:10.5455/apd.178087





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